The study looked at the genetic makeup of the disease in samples from over 1,500 patients with AML. After detailed genetic analysis they found that AML could be subdivided into 11 distinct diseases, each with their own set of genetic changes and specific clinical symptoms. Using this information doctors will be able to better identify those patients most likely to respond well to current treatment and those who may be at higher risk of relapse.
Dr Elli Papaemmanuil believes that “by understanding these paths we can help develop more appropriate treatments for individual patients with AML."
Co-author, Dr Campbell said he hoped this technique would "filter into clinics" over the next few years as more centres develop their diagnostic resources.